Journal: Scientific Reports
Article Title: The role of GRK6 in animal models of Parkinson's Disease and L-DOPA treatment
doi: 10.1038/srep00301
Figure Lengend Snippet: After 30 minutes of habituation, all groups received αMT 250 mg/kg, i.p. and 1 hour later they received an injection of L-DOPA/Carbidopa 10/10 mg/kg, i.p. followed by of L-DOPA 20 mg/kg, i.p. one hour later (4A). A second group of animal was treated with 30/10 mg/kg, i.p. of L-DOPA/Carbidopa (4B). Statistical analysis: One-Way Anova for repeated measures, Bonferroni post hoc analysis. *p<0.05 vs DDD mice at the same time point.
Article Snippet: All the drugs used for this work were purchased from Sigma Aldrich (Milan, Italy) with exception of Carbidopa ((S)-(-)-Carbidopa, Tocris, Bristol, UK) and amphetamine (Poole, UK).
Techniques: Injection